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dc.contributor.authorRohmah, Miftakhur
dc.contributor.authorRahmadi, Anton
dc.contributor.authorRaharjo, Sri
dc.date.accessioned2022-03-24T04:31:57Z
dc.date.available2022-03-24T04:31:57Z
dc.date.issued2022
dc.identifier.urihttp://repository.unmul.ac.id/handle/123456789/36192
dc.description.abstractβ-carotene (βC) is an essential nutrient for health. It is a potent antioxidant, anti-cancer, and anti-inflammatory substance. However, βC has high hydrophobicity property, indicating a low absorption level in the digestive tract. The bioavailability of βC is reasonably low. Lipid-based delivery systems such as nanostructured lipid carriers (NLC) potentially can help to overcome this problem. This research evaluated the bioaccessibility of the nanostructured mixture of palm stearin (PS) and palm olein (PO) and the antioxidant activity of βC in the structure. β-carotene bioaccessibility was studied by measuring the micellization during in vitro digestion. Anti oxidants activity was measured by 2.20-azino-bis (3-ethylbenzothiazoline- 6-sulphonic acid) (ABTS) and 2, 2 –diphenyl -1- picrylhydrazyl (DPPH) reduction methods. In vitro gastrointestinal digestion model indicated that nanostructured lipid carrier enhanced bioaccessibility and antioxidants activity of βC. This suggests that the formulated NLC system can be used effectively to deliver lipophilic bioactive such as βC in beverage products.en_US
dc.publisherCellPressen_US
dc.subjectβ-caroteneen_US
dc.subjectNanostructured lipid carriers (NLC)en_US
dc.subjectPalm stearinen_US
dc.subjectPalm oleinen_US
dc.subjectBioaccessibilityen_US
dc.subjectAntioxidant activityen_US
dc.titleBioaccessibility and antioxidant activity of β-carotene loaded nanostructured lipid carrier (NLC) from binary mixtures of palm stearin and palm oleinen_US
dc.typeArticleen_US


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