dc.contributor.author | Sedionoto, Blego | |
dc.date.accessioned | 2024-01-03T05:30:18Z | |
dc.date.available | 2024-01-03T05:30:18Z | |
dc.date.issued | 2023-07-29 | |
dc.identifier.citation | - | en_US |
dc.identifier.uri | https://www.journalaji.com | |
dc.identifier.uri | http://repository.unmul.ac.id/handle/123456789/55732 | |
dc.description | - | en_US |
dc.description.abstract | Aims: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) as a tool for evaluating immunoreactivity against cobalt in patients with clinical suspicion of cobalt hypersensitivity.
Study Design: We retrospectively examined the medical charts of a population of 97 patients diagnosed with Allergic Contact Dermatitis (ACD) and/or dyshidrotic eczema (DE) with clinical suspicion of cobalt hypersensitivity who were investigated with an ex vivo challenge monitored by LAIT against CoCl₂·6H₂O.
Place and Duration of Study: Instituto Alergoimuno de Americana – São Paulo – Brazil – between January 2018 and June 2023.
Methodology The percentage of Leukocyte Adherence Inhibition (LAI) promoted by the ex vivo challenges with CoCl₂·6H₂O was distributed in ranges through Cascade Distribution Charts to observe the variability of the results.
Results: The LAI mean was 44.8%, SD 26.9%, range 0% to 94%, mode = 0% (appeared 14 times). There was a wide range of distribution of LAI results, suggesting that some patients had immunoreactivity against cobalt, while others do not.
Conclusion: Our preliminary results support the fact that the LAIT performed with CoCl₂·6H₂O may differentiate diverse degrees of ex vivo immunoreactivity against cobalt in allergic patients. | en_US |
dc.description.sponsorship | - | en_US |
dc.language.iso | en | en_US |
dc.publisher | Asian Journal of Immunology | en_US |
dc.relation.ispartofseries | -;- | |
dc.subject | Cobalt, Dermatitis, allergic contact, Dermatitis, contact, Diagnosis, Eczema, dyshidrotic, Leukocyte Adherence Inhibition Test, Skin tests. | en_US |
dc.title | Contribution of the Leukocyte Adherence Inhibition Test to the Diagnosis of Immunoreactivity against Cobalt | en_US |
dc.title.alternative | - | en_US |
dc.type | Other | en_US |