Antidiabetic Activity of leaf extract from three types of Mangrove Originating from Sambera Coastal Region Indonesia
Abstract
This study designed to determine the antidiabetic profile ethanol extracts of leaf extract from three types of mangroves; Avicennia sp., Rhizopora sp, and
Sonneratia sp. Extraction process used maceration with ethanol solvent. The phytochemical assayis carried out qualitatively including assay of alkaloids
flavonoids, steroids, terpenoids, phenolic compounds, tannins, and saponins. The method used for the antidiabetic test is the method of blood glucose tolerance
The results showed that ethanol extract of three types of mangrove leaves Avicennia sp., Rhizopora sp, and Sonneratia sp. containing secondary metabolite group
alkaloids, flavonoids, steroids, terpenoids, phenolic compounds, tannins, and saponins. Ethanol extract of leaves of the three types of mangroves plants has
antidiabetic activity. The ethanol extract of leaves of mangrove Rhizophora sp. with a dose of 200 mg/kg BB + glucose 2 g / kg (group P-2) showed the most excellen
antidiabetic activity and lowering blood glucose levels by 31.27%. This study confirmed that three types of Mangrove from Sambera Coastal Region Indonesia
showed the antidiabetic profile.
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