| dc.contributor.author | Mulyani, Melia | |
| dc.contributor.author | Farah, Harra Ismi | |
| dc.contributor.author | Rusli, Rolan | |
| dc.contributor.author | Rahmadani, Agung | |
| dc.date.accessioned | 2022-01-17T12:27:29Z | |
| dc.date.available | 2022-01-17T12:27:29Z | |
| dc.date.issued | 2021-09-28 | |
| dc.identifier.issn | 1551-7616 | |
| dc.identifier.uri | http://repository.unmul.ac.id/handle/123456789/12819 | |
| dc.description.abstract | This study was aimed to synthesis the chalcone derivative and tested its toxicity. Synthesis of 2'-hydroxy-5'-chloro-3,4-dimethoxychalcone carried out through Claisen Schmidt condensation at room temperature. The toxicity test prepared by Bhrine Shrimp Lethality Test (BSLT) to Artemia salina L. Analysis retrosynthetic gives the 2-hydroxy-5-chloro acetophenone and 3,4-dimethoxy benzaldehyde as starting materials. The desire chalcone was confirmed by 1H-NMR and 13C-NMR, also mass spectroscopy. The chalcone obtained in 83,27% and exhibited LC50 value in 974,99 ug/mL. | en_US |
| dc.publisher | AIP Conference Proceedings | en_US |
| dc.relation.ispartofseries | 2360;050023 | |
| dc.subject | Synthesis, toxicity, 2'-hydroxy-5'-chloro-3,4-dimethoxychalcone | en_US |
| dc.title | Synthesis and toxicity test of 2’-hydroxy-5’-chloro-3,4-dymethoxychalcone | en_US |
| dc.type | Article | en_US |
