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Please use this identifier to cite or link to this item: http://repository.unmul.ac.id/handle/123456789/478
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dc.contributor.authorMarliana, Eva
dc.contributor.authorAstuti, Winni
dc.contributor.authorKosala, Khemasili
dc.contributor.authorHairani, Rita
dc.contributor.authorTjahjandarie, Tjitjik Srie
dc.contributor.authorTanjung, Mulyadi
dc.date.accessioned2019-10-18T15:14:35Z
dc.date.available2019-10-18T15:14:35Z
dc.date.issued2018
dc.identifier.issn0975-427X
dc.identifier.urihttp://repository-ds.unmul.ac.id:8080/handle/123456789/478
dc.description.abstractThe anticancer activity of methanolic ectract and ethyl acetate fraction of Macaranga hosei leaves against HeLa cell lines were evaluated by [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT) assay. Both extracts displayed anticancer activity with IC50 value of 36.18 and 7.01 µM, respectively, which can be suggested that M. Hosei is a great potential source of anticancer agents. In addition, two isoprenylated flavanones, 4’-O-methyl-8-isoprenyl eriodictyol (1) and 6-isoprenyl eriodictyol (2) have been isolated from ethyl acetate fraction. The structures of both compounds have been elucidated based on their spectroscopic data, including 1D and 2D NMR spectra. Keywords: Macaranga hosei, Anticancer, MTT Assay, Flavanones, Isoprenylated
dc.publisherAsian Journal of Chemistry
dc.titleChemical Composition and Anticancer of Macaranga hosei Leaves
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