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Please use this identifier to cite or link to this item: http://repository.unmul.ac.id/handle/123456789/39981
Title: Cochlioquinone derivatives produced by coculture of endophytes, Clonostachys rosea and Nectria pseudotrichia
Authors: Supriatno, Salam
Keywords: Nectrianolin Endophyte Cytotoxicity Coculture Furanocochlioquinone Furanocochlioquinol
Issue Date: 3-Oct-2021
Publisher: Fitoterapia
Abstract: Three new meroterpenoid derivatives, furanocochlioquinol (1) and furanocochlioquinone (2), as well as nectrianolin D (3), together with two known biogenetically related compounds 4 and 5 were isolated from a mixed culture of two mangrove-derived fungi, Clonostachys rosea B5–2 and Nectria pseudotrichia B69–1. The structures of 1–3 were deduced based on the interpretation of HRMS and NMR data. Compounds 1–5 exhibited cytotoxicity against human promyelocytic leukemia (HL60) cells with IC50 values ranging from 0.47 to 10.16 μM.
URI: http://repository.unmul.ac.id/handle/123456789/39981
Appears in Collections:A - Pharmacy

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