Turnitin Chemical Composition and Anticancer Activity of Macaranga hosei Leaves

Please use this identifier to cite or link to this item: http://repository.unmul.ac.id/handle/123456789/3423

Title:	Turnitin Chemical Composition and Anticancer Activity of Macaranga hosei Leaves
Authors:	Kosala, Khemasili Marliana, Eva Astuti, Winni Hairani, Rita Tjahjandarie, Tjitjik Srie Tanjung, Mulyadi
Keywords:	Macaranga hosei, anticancer, MTT Assay, Flavonone, Isoprenylated.
Issue Date:	28-Feb-2018
Publisher:	Chemic Publishing Co. Asian Journal of Chemistry, Vol 30 no. 4 2018. 795-798
Citation:	Marliana E, Astuti W, Kosala K, Hairani R, Tjahjandarie TS, Tanjung M. 2018. Chemical Composition and Anticancer Activity of Macaranga hosei Leaves. Asian J. Chem. 30(4):795-798
Abstract:	The anticancer activity of methanolic extract and ethyl acetate fraction of Macaranga hosei leaves against HeLa cell lines were evaluated by [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT) assay. Both extracts displayed anticancer activity with IC50 values of 36.18 and 7.01 uM, respectively, which can be suggested that M.hosei is a great potential source of anticancer agents. In addition, two isoprenylated flavonones, 4'-O-methyl-8-isoprenyl eriodictyol (1) and 6-isoprenyl eriodictyol (2) have been isolated from ethyl acetate fraction. The structures of both compounds have been elucidated based on their spectroscopic data, including 1D and 2D NMR spectra.
URI:	http://repository.unmul.ac.id/handle/123456789/3423
ISSN:	09707077
Appears in Collections:	Yunita Rahma

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