Immunomodulatory and antibacterial effects of Boesenbergia pandurata, Solanum ferox, and Zingiber zerumbet on tilapia, Oreochromis niloticus

Abstract

The aims of the study were to evaluate the potency of antibacterial and immunostimulant effects of some herbs extract, that is, Boesenbergia pandurata, Solanum ferox, and Zingiber zerumbet from East Kalimantan on tilapia Oreochromis niloticus infected by Aeromonas hydrophila and Pseudomonas sp. The focus of this study was to determine the most effective dosage and method of administration to prevent the bacterial infection by in vivo test. Thirty tilapias with the average weight of 15 g were used in this experiment. The tested dosages extracts were 600 ppm B. pandurata, 900 ppm S. ferox, and 200 ppm Z. zerumbet. Meanwhile, three administration methods were applied, that is, injection method, feeding and bath immersion. The results showed that the extract of B. pandurata, S. ferox, and Z. zerumbet can be used as an antibacterial and immunostimulant compound in tilapia. The B. pandurata and Z. zerumbet extracts effectively were used to prevent A. hydrophila infection using the feed method while S. ferox extract effectively prevented Pseudomonas sp. infection by bath immersion.