Synthesis and toxicity test of 2’-hydroxy-5’-chloro-3,4-dymethoxychalcone

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DC Field	Value	Language
dc.contributor.author	Mulyani, Melia	-
dc.contributor.author	Farah, Harra Ismi	-
dc.contributor.author	Rusli, Rolan	-
dc.contributor.author	Rahmadani, Agung	-
dc.date.accessioned	2022-01-17T12:27:29Z	-
dc.date.available	2022-01-17T12:27:29Z	-
dc.date.issued	2021-09-28	-
dc.identifier.issn	1551-7616	-
dc.identifier.uri	http://repository.unmul.ac.id/handle/123456789/12819	-
dc.description.abstract	This study was aimed to synthesis the chalcone derivative and tested its toxicity. Synthesis of 2'-hydroxy-5'-chloro-3,4-dimethoxychalcone carried out through Claisen Schmidt condensation at room temperature. The toxicity test prepared by Bhrine Shrimp Lethality Test (BSLT) to Artemia salina L. Analysis retrosynthetic gives the 2-hydroxy-5-chloro acetophenone and 3,4-dimethoxy benzaldehyde as starting materials. The desire chalcone was confirmed by 1H-NMR and 13C-NMR, also mass spectroscopy. The chalcone obtained in 83,27% and exhibited LC50 value in 974,99 ug/mL.	en_US
dc.publisher	AIP Conference Proceedings	en_US
dc.relation.ispartofseries	2360;050023	-
dc.subject	Synthesis, toxicity, 2'-hydroxy-5'-chloro-3,4-dimethoxychalcone	en_US
dc.title	Synthesis and toxicity test of 2’-hydroxy-5’-chloro-3,4-dymethoxychalcone	en_US
dc.type	Article	en_US
Appears in Collections:	P - Pharmacy

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