dc.contributor.author | Mahyati, Agus | |
dc.contributor.author | Koesnarpadi, Soerja | |
dc.contributor.author | Erwin | |
dc.date.accessioned | 2022-01-14T13:09:37Z | |
dc.date.available | 2022-01-14T13:09:37Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 2549-0052 | |
dc.identifier.uri | http://repository.unmul.ac.id/handle/123456789/9594 | |
dc.description.abstract | Magnetite is widely used in various fields of separation, biochemistry, medical and environment.
Modification of nanoparticle magnetite binding with chitosan is recommended for many biomedical applications,
especially as a drug delivery system because in addition to its non-toxic, biodegradable and biocompatible
characteristics. Another advantage of biomedical benefits as antimicrobial is that it can increase antibacterial
activity and has a more pronounced effect on gram-negative and gram-positive bacteria. Synthesis and
characterization of chitosan-magnetite cross-linked tripolyphosphate as an antibacterial of S. typhi (Gram negative)
and S. aureus (Gram positive) has been carried out. The phase of this research was initiated by the synthesis of
FeSO4.7H2O and FeCl3.6H2O magnetite with a mass ratio of Fe (II): Fe (III) = 2: 3, using the co-precipitation
method. In the second stage where the cross-linking of chitosan with TPP cross-linker to form ferrogel. In the third
stage the synthesis of TPP-chitosan-magnetite in a ratio of 1: 4, with a slight addition of NH4OH as participant
material. The results showed that FT-IR on TPP-chitosan-magnetite has a unique spectrum, XRD results showed
the crystal structure of TPP-chitosan-magnetite did not change. Surface morphology shows that TPP-chitosanmagnetite is a spherical surface. Chitosan-Magnetite material has greater antibacterial activity than chitosan and
magnetite bacteria S. typhi (Gram negative) and S. aureus (Gram positive). | en_US |
dc.publisher | Jurnal Atomik | en_US |
dc.relation.ispartofseries | Vol 6;No 1 | |
dc.subject | Magnetite (Fe3O4), Chitosan-Tripolyphosphate-Magnetite, Tripolyphosphate (TPP) Cross-Linker, Salmonella typhi, Staphylococus aureus | en_US |
dc.title | SYNTHESIS OF CHITOSAN-MAGNETITE NANOPARTICLES CROSS-LINKED TRIPOLYPHOSPHATE AS ANTIBACTERIAL Salmonella typhi AND Staphylococcus aureus | en_US |
dc.title.alternative | SINTESIS NANOPARTIKEL KITOSAN-MAGNETIT TERSAMBUNG SILANG TRIPOLIFOSFAT SEBAGAI ANTIBAKTERI Salmonella typhi DAN Staphylococcus aureus | en_US |
dc.type | Article | en_US |