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dc.contributor.authorCandra, Krishna Purnawan
dc.contributor.authorWardhani, Wijayanti Kusuma
dc.contributor.authorRahmadi, Anton
dc.contributor.authorMiftakhur, Rohmah
dc.contributor.authorYuliani, Yuliani
dc.date.accessioned2020-10-13T06:04:40Z
dc.date.available2020-10-13T06:04:40Z
dc.date.issued2020-10-01
dc.identifier.issn2541-4062
dc.identifier.issn1411-8513
dc.identifier.urihttp://repository.unmul.ac.id/handle/123456789/4982
dc.description.abstractFrangipani flower (Plumeria accuminata) and bitter grape (Tinospora crispa L. Miers) stem extract alone shows antimicrobial and antioxidant activities. However, there is a limited report about the actions from the combination of both extracts. Combinations of ethanol extract of white frangipani flower (EFF) and ethanol extract of the bitter grape stem (EBS), each of 0, 1, 2, and 3% were tested for inhibition against Staphylococcus aureus growth and DPPH (1,1-diphenyl,2-picrylhydrazyl) free radicals. A yield of 3.17 and 2,62 g of EFF and EBS, respectively, were resulted from 100 g of dried powdered of the white frangipani flower and bitter grape stem using 200 mL of absolute ethanol. The antimicrobial test was assayed using a 10% stock solution of extract diluted in water. The combination of EFF and EBS showed a synergistic effect on antimicrobial activity, but it proved an antagonistic effect on antioxidant activity. The combination of EFF 3% and EBS 3% showed the highest inhibition index on the S. aureus growth , i.e. 2.02±0.06, which is higher than the inhibition index of Amoxycillin 2%, i.e. 1.85±0.09. The highest antioxidant activity showed by 1% EFF alone (57.5 ± 0.60%), while the lowest was from the combination of EFF 1% and EBS 3% (23.4±0.30%).en_US
dc.language.isoenen_US
dc.publisherFMIPA Universitas Syiah Kualaen_US
dc.subjectPlumeriaen_US
dc.subjectbitter grapeen_US
dc.subjectTinosporaen_US
dc.subjectStaphylococcus aureusen_US
dc.titleStudy of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activitiesen_US
dc.typeArticleen_US


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