A new antiplasmodial sterol from Indonesian marine sponge, Xestospongia sp

dc.contributor.author	Supriatno, Salam
dc.date.accessioned	2022-08-18T14:28:01Z
dc.date.available	2022-08-18T14:28:01Z
dc.date.issued	2019-04-21
dc.identifier.uri	http://repository.unmul.ac.id/handle/123456789/39993
dc.description.abstract	A new antimalarial sterol, kaimanol (1), along with a known sterol, saringosterol (2) was isolated from the Indonesian Marine sponge, Xestospongia sp. The chemical structure of the new compound was determined on the basis of spectroscopic evidences and by comparison to those related compounds previously reported. Isolated compounds, 1 and 2 were evaluated for their antiplasmodial effect against Plasmodium falciparum 3D7 strains. Compounds 1 and 2 exhibited antiplasmodial activity with IC50 values of 359 and 0.250 nM, respectively.	en_US
dc.language.iso	en	en_US
dc.publisher	NATURAL PRODUCT RESEARCH	en_US
dc.subject	Xestospongia sp; sterol; kaimanol; Plasmodium falcifarum; Petrosiidae	en_US
dc.title	A new antiplasmodial sterol from Indonesian marine sponge, Xestospongia sp	en_US