Cochlioquinone derivatives produced by coculture of endophytes, Clonostachys rosea and Nectria pseudotrichia

dc.contributor.author	Supriatno, Salam
dc.date.accessioned	2022-08-18T14:02:17Z
dc.date.available	2022-08-18T14:02:17Z
dc.date.issued	2021-10-03
dc.identifier.uri	http://repository.unmul.ac.id/handle/123456789/39981
dc.description.abstract	Three new meroterpenoid derivatives, furanocochlioquinol (1) and furanocochlioquinone (2), as well as nectrianolin D (3), together with two known biogenetically related compounds 4 and 5 were isolated from a mixed culture of two mangrove-derived fungi, Clonostachys rosea B5–2 and Nectria pseudotrichia B69–1. The structures of 1–3 were deduced based on the interpretation of HRMS and NMR data. Compounds 1–5 exhibited cytotoxicity against human promyelocytic leukemia (HL60) cells with IC50 values ranging from 0.47 to 10.16 μM.	en_US
dc.language.iso	en	en_US
dc.publisher	Fitoterapia	en_US
dc.subject	Nectrianolin Endophyte Cytotoxicity Coculture Furanocochlioquinone Furanocochlioquinol	en_US
dc.title	Cochlioquinone derivatives produced by coculture of endophytes, Clonostachys rosea and Nectria pseudotrichia	en_US