Application of Ionic Liquid based MicrowaveAssisted Extraction of the Secondary Metabolite from Peperomia pellucida (L) Kunth
Abstract
Introduction: An ionic liquid (ILs) is a new alternative solvent (containing cations and anions) has the physical
and specifc solutions properties, and also had proven to be a promising substituent of conventional organic
solvents are ?ammable, volatile and toxic in various processes. The ILS application in separating the secondary
metabolites compound from Peperomia pellucida (L) Kunth herbaceous can be carried out using microwaveassisted extraction method (MAE). Objective: The aim of this study was to investigate the effect of ionic liquid
based microwave-assisted extraction method for attracting the secondary metabolites compound from P. pellucida compared with a conventional solvent for the enrichment of secondary metabolites (especially polyphenols
group) and their HPTLC fngerprinting profle. Methods:The herb dried powder extracted by microwave-assisted
extraction using an ionic liquid such us 1-Butyl-3-methylimidazolium chloride ([BMIM]Cl), 1-Butyl-3-methylimidazolium Bromide ([BMIM]Br). The obtained extract solution was partitioned using an organic solvent; the extract
was evaporated to obtain a dry extract and determination the HPTLC fngerprinting profle. Results: Based on
the research results was obtained from the various types of solvents there are differences in the extraction of
secondary metabolite.
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