| dc.date.accessioned | 2022-01-18T06:44:16Z | |
| dc.date.available | 2022-01-18T06:44:16Z | |
| dc.date.issued | 2020-09-01 | |
| dc.identifier.citation | Sulistiarini, 2020, Anticancer Activity of Fibraurea Tinctoria with DLD1 Celline Cytotoxicity Assay | en_US |
| dc.identifier.uri | http://repository.unmul.ac.id/handle/123456789/14284 | |
| dc.description.abstract | This study aims to determine the cytotoxic effects of Fibraurea tinctorial plants on DLD1 colon cancer cell
lines in vitro and determine the IC50 values of these plants. The test begins with cell-line culture in the DMEM
medium. Cultures that were ready with an estimated concentration in fresh media of 2.5x 104cells / 200uL
were exposed to 0.4uL test material in 0.1% DMSO with concentrations starting at 6.25 ppm; 12.5 ppm; 25
ppm; 50 ppm; 100 ppm; 200ppm; 400ppm; 800ppm; and 1600ppm which was then incubated for 48 hours.
The results are from methanol extract, hexane fraction, ethyl acetate fraction and HA and HB subfraction
from Fibraurea tinctorial plants, only HB subfaction which shows inhibitory activity against DLD1 colon
cancer cell line with 28% at 1600 ppm concentration. | en_US |
| dc.description.sponsorship | Thank you to the Samboja East Kalimantan Natural
Resources Conservation Center for plant
identification, Pharmacy of Faculty Mulawarman
University for learning opportunities, Biotechnology
centre of BPPT Serpog for activity testing facilities
for cell line dld1, Indonesian Ministry of Finance
Ministry of Education Funding Scholarship
Management Institute for financial assistance, and for
the Pharmacy School of the Bandung Institute of
Technology for research facilities. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | y SCITEPRESS – Science and Technology Publications, Lda | en_US |
| dc.subject | Anticancer, DLD1 Cel line, Cytotoxicity Assay | en_US |
| dc.title | Anticancer Activity of Fibraurea Tinctoria with DLD1 Celline Cytotoxicity Assay | en_US |
| dc.type | Article | en_US |
