http://repository.unmul.ac.id/handle/123456789/1467 2026-07-03T02:40:48Z http://repository.unmul.ac.id/handle/123456789/55923 CRISPR-CAS9 System: Teknologi Terbaru Genome Editing sebagai Terapi Penyakit Rongga Mulut di Masa Depan Latar Belakang: CRISPR (Clustered Regularly InterSpaced PalindromicRepeats) merupakan teknologi yang terbukti mampu memodifikasi,memperbaiki, dan mengganti komponen gen (genome editing). Sistem inibergantung pada enzim Cas9 (protein-9 nuklease terkait CRISPR) dan gRNA(panduan asam ribonukleat). Berbagai penyakit yang berhubungan dengangen tertentu dalam genom manusia juga berhubungan dengan kondisimulut. Tujuan: Tinjauan literatur digunakan dalam penelitian ini untukmenjelaskan potensi penerapan teknologi CRISPR/Cas9 sebagai terapipenyakit mulut di masa depan. Pembahasan: Penerapan CRISPR/Cas9 dapatmengarah pada identifikasi kerusakan gen dan penemuan gen yangmelawan gen pemicu tumor yang menyebabkan kanker mulut. Selain itu,memiliki kegunaan dalam kasus infeksi mikroorganisme di rongga mulut,seperti menargetkan gen penyandi glikosiltransferase pada Streptococcusmutans. Gangguan ini mengganggu sintesis matriks EPS (zat polimerekstraseluler), sehingga menghambat pembentukan biofilm. Kesimpulan: Efektivitas CRISPR/Cas9 dalam mengubah populasi bakteri atau gen yangsalah memberikan peluang untuk mengatasi penyakit mulut yang rumit,yang berpotensi merevolusi perawatan gigi. Namun, meskipun menjanjikan,uji klinis yang melibatkan teknologi ini masih berada pada tahap awal danrelatif tidak jelas, terutama dalam bidang kedokteran gigi. Oleh karena itu,kumpulan literatur yang komprehensif sangat penting untuk menumbuhkanpemahaman dan kesadaran akan kemajuan inovatif ini. 2023-10-08T00:00:00Z http://repository.unmul.ac.id/handle/123456789/43279 The Development of Sport Talent Identification Model-Software Sport Search-Based: To Support Program Design of National Sport Muhammad, Ramli Buhari 2022-11-15T00:00:00Z http://repository.unmul.ac.id/handle/123456789/32286 THE SPIRITUAL DIMENSION OF THE CONCEPT OF MAKING MOSQUE PROSPERITY AGAINST TRUST IMPROVEMENT SOCIETY FOR ZISWAF Kamaruddin, Andi Martina This study aims to build a spiritual dimension of the concept of prospering mosques in managing mosque funds so that they can increase and maintain public trust in tithe, donations, and alms at the Pelita Grand Mosque in Samarinda. The methodology used in this research is the religionist method. The informants in this study were the Takmir of Pelita Mosque Samarinda, which included the Secretary of Mosque, the Treasurer of Mosque, and the Head of Education Section of Pelita Mosque Samarinda, as well as the congregation of the Pelita Mosque Samarinda. Data collection techniques used were interviews, library sources, and documentation. The results of this study indicate that the spiritual dimension of the concept of prospering a mosque has a scope, namely faith, the hereafter, the internalization of prayer and zakat, and management. This dimension raises managerial principles in the mosques management so that it is vital in increasing public trust in giving zakat, donations, and alms at the Pelita Mosque Samarinda. The contribution of this research includes being able to expand the conceptual benchmark dimensions of prospering the mosque so that it can improve the quality and responsibility of the mosque takmir in terms of managing mandates, especially for people who have distributed ZISWAF funds. Keywords: Prosperity; Pelita Mosque Samarinda; Takmir Masjid; At-Taubah - 2020-07-19T00:00:00Z http://repository.unmul.ac.id/handle/123456789/7973 Multi-ethnic communities adaptation to flooding in the north samarinda sub-district, samarinda city, east kalimantan province, indonesia Answar, Yaskinul Samarinda as the capital city of East Kalimantan is a city that has a fairly rapid growth and also a place for migrants which has caused the city to be inhabited by various ethnic groups. Samarinda City is a city that always floods every year. One area of Samarinda City which often floods is the North Samarinda Sub-district. This paper tries to explore how the adaptation of multi-ethnic immigrant communities to floods. Data collection techniques used the Rapid Rural Appraisal (RRA) method and interviews. The results showed that the overall adaptation carried out by the community in North Samarinda Subdistrict was to raise the floor of the house, build a house on stilts, and make dikes. The shape of the house on stilts is a form of adaptation of the Bugis and Banjar tribes while the Javanese, Madurese and Mandar tribes only raise the floor of the house and make dikes. Based on the knowledge of local wisdom or the customs given from the ancestors, none of the respondents possessed one, which was caused by the absence of flood experience in the original place or because of the influence of modernization. 2021-03-01T00:00:00Z