Membrane stabilization activity as anti-inflammatory mechanisms of Vernonia amygdalina leaves extracts
dc.contributor.author | Nuryanto, MK | |
dc.contributor.author | Paramita, Swandari | |
dc.contributor.author | Iskandar, Abdillah | |
dc.date.accessioned | 2019-10-19T03:08:31Z | |
dc.date.available | 2019-10-19T03:08:31Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1755-1315 | |
dc.identifier.uri | http://repository-ds.unmul.ac.id:8080/handle/123456789/907 | |
dc.description.abstract | Inflammation is a normal process in the human body as a response to injury from the healing process. Meanwhile, chronic inflammation will cause new health problems for patients. Anti-inflammatory agents generally used for those conditions, have several side effects on patients. The aim of this research was to find alternative anti-inflammatory agents, especially from natural sources. Vernonia amygdalina knew locally as “daun afrika” belong to family Apiaceae is one of those potential natural sources for alternative anti-inflammatory agents. This plant is known as a traditional medicine from East Kalimantan for health problems caused by the muscle stiffness and used as the material in this research. The experimental method of anti-inflammatory measurement using membrane stabilization activity for V. amygdalina leaves extracts. The results showed that significant differences of EC50(p<0.05)achieved between indomethacin as the positive control (26.39 ± 2.91 ?g/mL) with V. amygdalina leaves extracts for concentration 1% (131.81 ± 2.95 ?g/mL) and 10% (62.54 ± 2.05 ?g/mL). EC50 of V.amygdalina leaves extracts showed the potential anti-inflammatory activities. It could be concluded that V. amygdalina leaves extracts to have anti-inflammatory activities, which could be further developed as a new natural source of the anti-inflammatory agents. | |
dc.publisher | 1st ICTROPS | |
dc.title | Membrane stabilization activity as anti-inflammatory mechanisms of Vernonia amygdalina leaves extracts |
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