| dc.description.abstract | Povidone iodine is an antiseptic that is often used for wounds after tooth extraction, but is often debated
because it can cause damage to cells and tissues. African leaf (Vernonia amygdalina Del.) from the family
Asteraceae has saponins as anti-microbial, anti-inflammatory and antioxidant flavonoids as that all may be
able to accelerate wound healing. To investigate the activity of extracts of Vernonia amygdalina folia (VAF)
to accelerate the process of wound healing after tooth extraction in rats. VAF extracted by maceration using
methanol. Wistar male rats as much as 6 groups (n = 5 mice each group) performed tooth extractions, and
then observed the reduction of gingival socket closure for 21 days after being given povidone iodine, distilled
water and methanol extract group VAF by 4 concentration. The closure of the wound after tooth extraction in
the group of povidone iodine rats occurred on the 8th day, the group aquadest cover the wound occurred on
the 12th day, the extract group 1, 3, 5, 7% sequentially occur wound closure on day 6th, 5th, 4th and 4th.
VAF methanol extract of the leaves can accelerate wound healing after tooth extraction of mice. | en_US |
