| dc.contributor.author | Kosala, Khemasili | |
| dc.contributor.author | Marliana, Eva | |
| dc.contributor.author | Astuti, Winni | |
| dc.contributor.author | Hairani, Rita | |
| dc.contributor.author | Tjahjandarie, Tjitjik Srie | |
| dc.contributor.author | Tanjung, Mulyadi | |
| dc.date.accessioned | 2019-12-27T02:44:43Z | |
| dc.date.available | 2019-12-27T02:44:43Z | |
| dc.date.issued | 2018-02-28 | |
| dc.identifier.citation | Marliana E, Astuti W, Kosala K, Hairani R, Tjahjandarie TS, Tanjung M. 2018. Chemical Composition and Anticancer Activity of Macaranga hosei Leaves. Asian J. Chem. 30(4):795-798 | en_US |
| dc.identifier.issn | 09707077 | |
| dc.identifier.uri | http://repository.unmul.ac.id/handle/123456789/3423 | |
| dc.description.abstract | The anticancer activity of methanolic extract and ethyl acetate fraction of Macaranga hosei leaves against HeLa cell lines were evaluated by [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT) assay. Both extracts displayed anticancer activity with IC50 values of 36.18 and 7.01 uM, respectively, which can be suggested that M.hosei is a great potential source of anticancer agents. In addition, two isoprenylated flavonones, 4'-O-methyl-8-isoprenyl eriodictyol (1) and 6-isoprenyl eriodictyol (2) have been isolated from ethyl acetate fraction. The structures of both compounds have been elucidated based on their spectroscopic data, including 1D and 2D NMR spectra. | en_US |
| dc.description.sponsorship | Ninistry of Research, Technology and Higher Education of Republic of Indonesia. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Chemic Publishing Co. Asian Journal of Chemistry, Vol 30 no. 4 2018. 795-798 | en_US |
| dc.subject | Macaranga hosei, anticancer, MTT Assay, Flavonone, Isoprenylated. | en_US |
| dc.title | Turnitin Chemical Composition and Anticancer Activity of Macaranga hosei Leaves | en_US |
| dc.type | Article | en_US |
